Based on the list of museums in Chongqing in 2018, this paper uses the method of nearest neighbor index, kernel density estimation, standard deviation ellipse,and geographic connection rate to analyze the structure type, spatial distribution, evolution characteristics and influencing factors of Chongqing museums.The research shows that the museums in Chongqing are rich in types, mainly including famous people, special subjects and comprehensive ones. There are obvious regional differences in spatial distribution, which are distributed along the main highways. From 1930 to 2018, Chongqing museums developed from random dots to cluster diffusion, with a significant trend of balance. western Chongqing area is in a circle, and the museums in northeast and southeast Chongqing are radiating. Natural conditions, historical culture, socioeconomic and policy conditions are the main factors affecting the distribution of museums in Chongqing.