| 摘要: |
| 以对氨基苯磺酸、亚硝酸钠和N,N-二甲基苯胺为原料，通过重氮化反应和偶合反应合成了甲基橙，比较了传统法合成甲基橙、常温下合成甲基橙、常温下水相介质中合成甲基橙;考察了反应物用量、反应温度、反应时间、溶液pH值和辅助剂对合成甲基橙的影响，得到了优化合成条件;结果表明:常温下水相介质中合成甲基橙反应过程时间最少、反应温度容易控制、产率最高，产品纯度好；其中N,N-二甲苯胺用量为1.3 mL，反应温度为20 ℃，反应时间为2 h，溶液pH值为6，辅助剂为乙醇或乙醚，在此条件下，甲基橙的最高产率可达87.09%; |
| 关键词: 甲基橙 重氮化 偶合 合成 |
| DOI： |
| 分类号: |
| 基金项目: |
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| Studies on Synthesis Method of Methyl Orange |
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HUANG Fei, QU Fei qiang, REN Xiao qiong
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| Abstract: |
| As raw material, p aminobenzene sulfonic acid, sodium nitrite and N,N dimethylaniline is used to synthesize methyl orange by diazotization and coupling reaction. The traditional method for the synthesis of methyl orange, synthesis of methyl orange at room temperature and at room temperature in water phase medium are compared. The dosage of the reactant, reaction temperature, reaction time, pH value of the solution and the adjuvant effect are studied and the optimized condition for the syntheses is found out. The experimental results show that the reaction time of synthesis of methyl orange at room temperature in water phase medium is shortest, reaction temperature is easily controlled, the yield is highest, and the product purity is highest. The dosage of N,N dimethylaniline is 1.3mL, the reaction temperature is 20℃, the reaction time is 2h, pH value of the solution is 6, the adjuvant is ethanol or ether, under which the methyl orange yield is up to 87.09%. The method can be applied in industrial production for easy operation with less reagent and energy consumption. |
| Key words: methyl orange diazotization coupling synthesis |
