The improvement of regional logistics capacity plays a crucial role in promoting the high-quality development of the regional economy. Considering the unbalanced development of regional logistics capacity in China, the four major urban agglomerations of Beijing-Tianjin-Hebei, Yangtze River Delta, Guangdong-Hong Kong-Macao, and Chengdu-Chongqing are selected as the research objects to analyze the current situation and existing problems of regional logistics capacity development in various regions. Ten indicators are selected from three levels of logistics demand capacity, logistics facilities and economic capacity, and logistics development potential to construct a comprehensive evaluation index system of regional logistics capacity. The entropy-TOPSIS comprehensive model is used to evaluate the regional logistics capacity of four major urban agglomerations in China. The differences in regional logistics capacity levels are analyzed and compared. The results show that the constructed evaluation index system can comprehensively and systematically reflect the current situation of regional logistics capabilities. The order of regional logistics capabilities of four major urban agglomerations is: Yangtze River Delta, Guangdong-Hong Kong-Macao, Beijing-Tianjin-Hebei, and Chengdu-Chongqing. Finally, suggestions for the development of regional logistics capabilities of the four major urban agglomerations are proposed.