The mass line is the magic weapon of the Communist Party of China to achieve the First Centenary Goal. It is also the magic weapon to achieve the Second Centenary Goal in the new era and new journey. “Doing everything for the masses” is the value purport of achieving the Second Centenary Goal. “Relying on the masses in every task” is the fundamental way to achieve the Second Centenary Goal. Carrying out the principle of “from the masses, to the masses” is the basic method to achieve the Second Centenary Goal. The path options for using the mass line to achieve the Second Centenary Goal include implementing the mass line through the whole process of people’s democracy, implementing the mass line in the process of promoting fairness and justice, and actively using new technological means to implement the mass line.