Based on the panel data of western provinces from 2010 to 2019 in China, a coupling coordina_x0002_tion degree model was established to comprehensively evaluate the degree of coordination between education and high-quality regional economic development. The results show that: the education index and regional economic high-quality development index of the western provinces have maintained a steady upward trend of fluctuation, but the development is uneven; the coupling coordination degree of the education and the high-quality development of regional economy in the western provinces also keeps an upward trend, but it is still at a relatively low level, indicating that the development of education in the west has significantly lagged behind the high-quality development of the regional economy. The low contribution of education to the high-quality development of the regional economy, the lack of educational investment incentives, the low degree of integration of production and education, and the lack of authorized patent achievements are the common shortcomings of 11 provinces including Sichuan province. Based on this, policy suggestions for promoting the coordinated development of education and regional economy in western China are put forward.