Chongqing， as an important node city in the Belt and Road Initiative and an important industrial base in the west of China， is now in a critical period of replacing old drivers of growth with new ones， transforming and upgrading its economy. Collaborative innovation between producer services and manufacturing plays an important role in adjusting and optimizing the industrial structure and improving economic quality and efficiency. In this context， firstly， domestic and foreign literatures related to the research topic are reviewed from the perspectives of “interactive integration” and “collaborative innovation” between producer services and manufacturing industries. Secondly， the mechanism of collaborative innovation between producer services and manufacturing industry is explained from three dimensions： spatial distribution， collaborative modes， and interactive relations. Thirdly， it analyzes the problems of collaborative innovation between producer services and manufacturing industry in Chongqing. Finally， considering the impact of the Belt and Road Initiative on collaborative innovation of these two industries， the optimization path is proposed.