In the process of promoting China’s economic growth，industrial agglomeration has been accompanied by some ecological problems，such as waste of resources，high energy consumption and direct discharge of pollutants，while the Yangtze River Economic Belt，as the leading demonstration zone of ecological civilization construction，has always been the most important to ecological environment protection.This paper，by taking 2006—2015 as the time limit，by taking T1，T2，T3，T4 and T5 five periods as the time scale，by taking the Yangtze River Economic Belt 108 above prefecturelevel cities as the spatial scale，from the Yangtze River Economic Belt，regional and city angle，by using the location entropy and the entropy value method，studies the decoupling relationship between industrial agglomeration and ecological environment by constructing Tapio decoupling index model and the catchup decoupling index model，and obtains the spatial distribution map of the decoupling relationship between the two by using ArcGIS10.4.