Based on the theory of social needs, comparison theory, setpoint theory, this paper explores the impact of vacation tour on quality of life, and confirms the causality relationship between vacation tour and quality of life by the pretestposttest experiment and by using the method of longitudinal study. The results show that the vacation tour is the reason for the improvement of the quality of life for the participants, and vacation tour can promote the quality of life of people, and vacation tourists have higher life satisfaction and happiness than nonvacation tourists. Finally, some suggestions are put forward.