Burnout is the physical and mental fatigue and exhaustion state which appears when an individual works under the severely working pressure and has become the common phenomenon in China’s tour guide industry. Based on an investigation of tour guides’ job burnout in Fuzhou City, this article uses factor analysis and single factor analysis of variance to analyze the real expression of the tour guides’ job burnout, uses clustering analysis to summarize the types of burnout and accordingly puts forward suggestions for the preventing and easing of the tour guides’ job burnout.