This paper uses regional entropy to recognize the leading industries of the five provinces in northwest China,selects the corresponding indicators to represent the agglomeration degree of the leading industries and the development level of logistics industry,uses entropy method to fit leading industry agglomeration degree index and logistics industry development level index of each province,has calculated the degree of order of above two indexes of each province,uses coupling coordination model to calculate the coupling coordination degree of the two during 2007—2017,and conducts analysis by combining the regression relation of the degree of order of the two indexes and their correlation of each province.The results show that,except Qinghai Province,the leading industry agglomeration degree and logistics industry development level of the other four provinces autonomus regions gradually become coordinated from non-coordination averagely,and also become coordinated from non-coordination in Qinghai if Qinghai eliminates three mining industries.Based on this,this paper points out that northwest areas should further promote the operating efficiency of logistics industry,enlarge the investment in logistics industry,strengthen regional cooperation and coordination of logistics industry,and try hard to boost the agglomerated development,transformation and upgrading of the regional leading industries.