From the perspective of ecosystem, the entrepreneurial ecosystem reveals the entrepreneurial subject, entrepreneurial elements, entrepreneurial environment and their interaction among various elements in the entrepreneurial ecosystem. Entrepreneurial ecosystem is a complex selfadaptive system, which has the various characteristics of complex selfadaptive system. From the system point of view, it has the systematic objectives, elements, operation mechanism and system boundary. In this paper, the connotation and extension of returning home entrepreneurship ecosystem for university graduates are threedimensionally analyzed from three aspects such as system objective, system elements and system operation mechanism by taking college graduates’ returning home entrepreneurship ecosystem as an example. At the same time, this paper analyzes the goal setting, the elements composition and the operation mechanism of the entrepreneurial ecosystem, and puts forward countermeasures and suggestions for strengthening the construction of the entrepreneurial ecosystem, which can provide reference for promoting the returning home entrepreneurship of university graduates and rural revitalization.