In recent years, more and more scholars pay attention to crossborder mergers and acquisitions of Chinese enterprises. In this paper, empirical test is used to analyze 432 crossborder M&A of Chinese enterprises from 2006 to 2012 in the perspective of political institution, economic institution and cultural institution. The result shows: In the aspect of political institution, Chinese enterprises tend to invest in countries that have improved political institution; In the aspect of economic institution, Chinese enterprises’ capital tends to flow into countries with free economic institution; In the aspect cultural institution, certain positive or negative relationship is not found between Chinese enterprises crossborder M&A location choice and the cultural distance between host country and China.