Yangtze River Economic Zone,which stretches across east,middle and west part of China and which is most developed valley economic zone of China,plays an important role in China's spatial development strategy.Urban economic development is the main content of Yangtze River Economic Zone.Based on quantitative model analysis of urban comprehensive competence of 41 cities across Yangtze River Economic Zone,this paper obtains total distribution and spatial segregation state of ur- ban comprehensive competence,and,according to this,gives a lot of suggestions for optimizing urban development of Yangtze River Economic Zone.