In Marx's early thoughts,he made many discussions on human essence and dissimilation,which are not only the interesting topics of philosophic research at that times but also are the amazing points which in- itiated Marx's whole theory.It is an inevitable logic for Marx to initially be deeply influenced by Feuerbach on discussing human essence and then on discussing dissimilation labor theory to demonstrate the essence of labor and,finally,to form human practice essence.Rationalizing the early theories of Marx on dissimilation and hu- man essence and then highly generalizing his theories in practice after deepening research are of great signifi- cance to our correctly understanding of real connotation of human essence of Marxism and of the whole philoso- phy of Marx.