As severe acute respiratory syndrome coronavirus 2 ( SARS -CoV- 2) is a global pandemic with exponential spread, effective antiviral drugs and vaccines are urgently needed to control and prevent the SARS-CoV -2 outbreak. Current challenge is to find and develop an effective and affordable drug for the treatment of SARS- CoV-2. Combining with the latest literature, this paper introduces the origin and species of coronavirus, the harm of human infection and the countermeasures. It is found that the active compounds of medicinal plants and other natural products are cheap and feasible in anti-SARS-CoV and enhancing immunity. Traditional Chinese medicine has also been proved the effectiveness of natural drugs in treating SARS-CoV. The active ingredients in natural products,such as plants,fungi and marine organisms may become new research objectives for the research and development of SARS-CoV-2 inhibitors.