For UAV selforganizing network, this paper proposes a high reliability routing algorithm based on geographic location information, GPSRHRU (High Reliability UAV Routing Algorithms Based on GPSR).Aiming at the characteristics of UAV such as fast moving speed, irregular movement, easy route breaking and hollow, MALM (Mobilityassisted Location Management)assisted location management strategy of mobile nodes is introduced into the GPSR protocol of wireless ad hoc networks to predict the mobile location of nodes.NS3 simulation of UAV working scene shows that the algorithm has lower transmission delay, more reliable endtoend delivery success rate and lighter load than GPSR algorithm and other improved algorithms.