In order to solve the problem of multiattribute decision making with interval value Pythagoras fuzzy number (IVPFN), a multiattribute decision making method based on interval value Pythagoras fuzzy cross entropy is proposed.Firstly, the concept of cross entropy is introduced into the intervalvalued Pythagoras fuzzy sets (IVPFS), and a new measure of cross entropy of the intervalvalued Pythagoras fuzzy sets (IVPFS) is defined ,which is used to describe the difference degree between the two intervalvalue Pythagoras fuzzy sets.Secondly, according to the score function of each interval value Pythagoras fuzzy number (IVPFN), the positive and negative ideal solutions of the interval value Pythagoras are determined.On the basis of TOPSIS principle, the optimal scheme is obtained according to the relative closeness between each scheme and the positive and negative ideal solution.Finally, an example is given to verify the proposed method, which shows its feasibility and rationality.