Abstract: Chalcones are p roducts of the cross2aldol condensation of ketones and aldehydes. Chalcones and their derivatives are important intemediates in organic synthesis and a variety of pharmacological effects and biologi2 cal activity. This article reviews all kinds of reaction system and systhesismethods in the recent years, introduces a variety of advantages of each reaction system and p roduction rate scope of synthesized Chalcone compounds and p re2 dicts that future flavones synthesis development direction is to use new technology, new methods and green synthesis without pollution.