Abstract: Rabies, which is also called lyssa, is a lethal contagious zoonotic disease by affecting the function of central nervous system. Once infected, clinical symp toms appear, the mortality is nearly 100 percent. Human and allwarm blooded animals can be in2 fected, wild animals are the natural host of rabies, but dogs and cats are the main hosts to carry and transmit rabies virus. Inrecent years, rabies shows increasing trend in China and rabies has become an important factor to affect and threat public health. Thus, learn2 ing the pathogeny characteristic, ep idemic situation, diagnosis, p revention and control is of great significance.