By studying the semiparametric varyingcoefficient partially nonlinear model with missing response at random， the parameters in the model are estimated. The unknown parameters in the model are estimated by combining the linear approximation with the spline estimating equations for varyingcoefficient partially nonlinear models with missing response at random， and the asymptotic properties of the resulting estimators are established. Finally， two simulations were conducted to test the procedures and assess the performance of the proposed estimating. The results show that the two procedures perform well in finite samples， with the increase of the sample size and the decrease of the missing rate， the accuracy of the estimation is improved.