Based on the measurement methods such as standard deviation, variation coefficient and Theil index, this paper analyzes the regional difference in tourism economy of Henan province during 2007—2014. the results show that the domestic tourism economy of Henan province demonstrates significant regional difference, that absolute difference multiply increases year by year, that the relative difference becomes gentle with small fluctuation and so on, that from 2007 to 2014, the unique fluctuation of interregion difference (［Tbr］) has a great influence on the intercity difference (Tp), which display a state of pancake hump while high intraregion difference (Twr) becomes the first cause for higher economic difference in domestic tourism of Henan province, that the average value of G and Z is 5% and 8% respectively, and that more than half of the cities in Henan province belong to the “civilian” city except 22% “noble” cities and 11% “rookie” cities.