Abstract:Human cerebral MRI data are acquired under resting state and sleep deprivation, the time sequence of functional magnetic resonance is extracted via wavelet transform, and the relativity of 116 human brain regions is calculated. This paper finds that human brain function connection has obvious change by comparing it with resting state under sleep deprivation, i.e., connection strength, clustering coefficient, feature path length, network efficiency and smallworld feature have significant change. Under sleep deprivation, cerebral regional point efficiency change activation in brain is increased, brain activation compensation is enhanced, however, in cerebellum region, point efficiency is significantly decreased, the impact on the number of cerebellum region is more than that of brain, which indicate that the effect of sleep deprivation on cerebellum regions is more obvious than that of brain regions.