According to the conventional meteorological data from 2011 to 2013 of Shapingba district in Chongqing, using MATLAB this paper analyzes the changes and features of the atmospheric mixing layer height in recent three years, and studies the correlation between meteorological parameters and atmospheric mixing layer height. The results show that during 8〖DK〗∶00-19〖DK〗∶00, atmospheric mixing layer height is positive correlation with the intensity of solar radiation, temperature, wind speed, negative correlation with pressure, relative humidity and no obvious correlation with the dew point temperature; during 20〖DK〗∶00-7〖DK〗∶00, atmospheric mixing layer height and intensity of solar radiation and wind speed is positively correlated, while it’s unobvious to correlate with other parameters. By using the meteorological data the prediction model of atmospheric mixed layer height in Chongqing is established and the accuracy is verified.