Based on the provincial panel data of three regions in the east, middle and west part of China during 1993-2012, this paper makes empirical analysis of the employment effect from the fixed assets investment of China from different regions, and the results show that there is obvious regional difference in the employment effect from the fixed assets investment of China, that the employment effect from the investment in the east part of China is significantly much higher than that of the middle and west part of China, in general, however, the rapid growth of the fixed asset investment does not result in the fast expansion of the employment, i.e., the fixed asset investment plays a limited role in driving the employment, and that in some provinces, there is a negative influence of the fixed asset investment increase on the employment.