North America has made great progress in structural genomics research,Europe is a slow start but strong finish in structural genomics research,Japan is one of the first countries to initiate strucral genomics and is making efforts to conduct it,and Australia is also participating in structural genomics research.Nucleic acid-bingding proteins are important to calrify the mechanism of nucleic acid-protein interaction for clearly explaining the mechanism of the pathogenesis of some disease by structural genomics research results so that the diseases,such as cancer,diabetes and so on,can be cured by the medicines synthesized according to the information of the related prorein structures.