摘要: |
摘 要:癫痫动物模型种类繁多,有电刺激点燃模型,化学点燃模型和遗传癫痫模型等多种癫痫模型,大
部分可以制备为难治性癫痫模型,对难治性癫痫的研究和治疗药物筛选提供了有力工具;现对不同癫痫模型
的制作方法、症状表现和发病机制等方面进行综述。 |
关键词: 癫痫 难治性癫痫 动物模型 |
DOI: |
分类号:R742.1 |
基金项目:重庆市教育委员会科学技术研究项目? |
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Research progress in intractabl seizure animalmodels |
KONG Shu - zhen, PENG Sen
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Abstract: |
Abstract: There are a variety of ep ilep tic animalmodels such as kindling ep ilep tic modelswith electrostimulation, chemical kin2
dling ep ilep tic models and inherited ep ilep tic models. Most of them are intractable ep ilep sy animal models and are useful for researc2
hing intractable seizure and screening effective drugs. This paper reviewsmakingmethods of different ep ilep tic models, their symp toms
and pathogenesis and so on. |
Key words: ep ilep sy intractable seizure animalmodel |