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| 摘要: |
| 壳聚糖是仅次于纤维素的天然多糖,因表面电荷密度高,毒副作用小,可生物降解,生物相容性好,兼具有强的生物粘附作用,使其在药物载体中具有独特的优势。主要介绍了壳聚糖微球作为药物载体常用的制备方法、释药特性、影响因素,以及在药物应用中的最新研究进展;指出了其在商品化方面亟须解决的问题。 |
| 关键词: 壳聚糖,微球,药学 |
| DOI： |
| 分类号:R914 |
| 基金项目: |
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| Application of chitosan microspheres as a potential carrier for drugs |
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REN Jian-min WU Si-wei
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| Abstract: |
| Chitosan is a biodegradable natural polymer with great potential for pharmaceutical applications due to its biocompatibility,high charge density,non-toxicity and mucoadhesion.It has been shown that it not only improves the disolution of poorly soluble dru |
| Key words: chitosan,microspheres,pharmacology |
