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| 摘要: |
| 计算机算法与实验技术相结合的方法,已广泛用于各种免疫相关抗原T细胞表位的鉴定,对现在可获得的计算机预测方法,以及计算机算法与实验相结合鉴定T细胞表位的方法进行了综述,主要内容包括表位预测及抗原加工处理的预测。 |
| 关键词: T细胞,表位预测,主要组织相容性复合物(MHC),计算机算法 |
| DOI: |
| 分类号:S858.31 TP301.6 |
| 基金项目: |
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| Combining computer algorithms with experimental approaches to screen T cell epitopes |
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WANG Hu-cheng
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| Abstract: |
| The identification of T cell epitopes from immunologically relevant antigens remains a critical step in the development of vaccines. This review presents an overview of strategies that combine computer algorithms with experimental approaches for the scree |
| Key words: T cell,epitope prediction,major histocompatibility complex (MHC),computer algorithm |