By reviewing the literatures from the field of economic growth theory, spatial economics and their combinational framework on regional disparity and China’s regional disparity, we find that the economic growth theory can reflect the dynamic evolution of regional disparity but is short of spatial dimension, that the traditional spatial economics has strong explanation capacity on the spatial distribution of economic activity but lacks of dynamical performance, that the two combination framework can embody the dynamic features and spatial dimension but is lacking of empirical analysis, based on this analysis, the future research should integrate dynamic features and spatial dimension simultaneously into regional disparity issue, emphasize the role of “knowledge-associated”factors such as technological progress, knowledge spillover and so on, further analyze the development direction of regional disparity and expand the empirical research methods under the combinational framework of innovative economic growth and spatial economics, etc.