Urban innovation spillover is limited by geographic distance, as a result, “center-edge” spatial pattern by regarding the cities which have strong innovative capacity as centers and the cities which have weak innovative capacity as edges is formed. New economic-geography spatial auto-correlation model is used to analyze spatial distribution characteristics of innovative capacity in 13 cities of Jiangsu Province, the results show that urban innovative capacity has obvious regional difference, that spatial distribution has important influence on innovative cities development, that relatively strong spatial dependence and difference between cities is demonstrated and that “core-edge” spatial distribution pattern in innovative clusters is initially formed. In order to realize fast and healthy development of innovative cities, China should break spatial limitation, enhance technical spillover effect between cities and promote self-innovative capacity.