The international and domestic background of strategic emerging industry selection and development as well as manufacturing industry determines that China must upgrade manufacturing industry to build the modern manufacturing system in China. The modern manufacturing system of China should be based on the main body function region and the large enterprises with international competitiveness, the breakthrough should depend on the strategic industries with advanced technology, high production efficiency, strong motivating of development and growth potential. Development momentum is increasing R&D input and continuously enhancing the high-quality technology innovation talents team. The ultimate objective should be to cultivate or create a series of the manufacturing enterprises and brands at international level, the construction of China’s modern manufacturing system should carry out brand strategy and core technology breakthrough.