Taking a firm’s cross - regional growth as an examp le, the author in this article analyzes the relationship of the firm’s cross- regional growth and the coordinated growth of cross - regional economy, and the motivation of the firm’s cross - regional growth.Countermeasures are p roposed that, by the agglomeration and diffusion effect, the cross - regional growth of a lot of large - sized firms will p romote the construction of industrial network and the economy agglomeration in the occup ied areas, and eventually create the coordination development of cross - regional economy and the united development of urban and rural areas.