Small and medium - sized enterprises play an important role in economic development. The financing of China's small and medium - sized enterprises has been concerned by theoretical and practical circles. This paper reveals that the financing of small and medium - sized enterprises is not only affected by the relative small scale when comparing with big enterprises but also is hampered by regional disadvantage because imbalanced regional financial development. This paper mainly analyzes financing condition of small and medium - sized enterprises of Sichuan Province, indicates that it has typical regional scale disadvantage and regional disadvantage in the process of financing and that it is worse when comparing them with the financing of small and medium - sized enterprises of coastal areas, uses real data statistics to make comparison and analysis from different angles and discusses the possible measures for gradually changing the disadvantages.