Technical innovation is decomposed into such three levels as technical innovation talent, technical innovation input and technical innovation achievement. Based on the relevant time series data of Chongqing during 1997-2013, this paper made an empirical research on the effect of the technical innovation on Chongqing’s economic growth by Solow growth model and Cobb-Douglas production function, cointegration test, GB test and ECM model and so on. The empirical results show that the innovation-driven power of Chongqing’s economic growth is fairly strong, but its position is not yet stable, factor-driven power and investment-driven power are still the main sources of its economic growth, that the technical innovation talents and input are the dominant force for its economic growth, however, the technical innovation achievement doesn’t have an obvious influence on its economic growth. Therefore, Chongqing should continue to deepen the reform of the science and technology system, introduce and cultivate more high-class science and technology talents, enhance the input on science and technology research, speed up the transformation of technical innovation achievements into real productivity and boost the transformation of factor-driven and investment-driven into innovation-driven for Chongqing’s economic development.