In order to quantitatively measure the coordination and adaptation level between regional talent training input and industrial economy output，by taking high-tech industry as empirical analysis object，the coupling evaluation model between highly-skilled talent cultivation input and high-tech industrial economic output is set up to measure the coordinated suitability of 31 provinces and municipalities by using panel data in 2010 of China. Evaluation results show that the coordinated suitability between highly-skilled talent cultivation input and high-tech industrial economic output reaches 0.478，stays on the verge of coupling detuning region and demonstrates unsatisfied result as a whole，that the input in highly-skilled talent cultivation is much higher than the economic output of high-tech industries in all provinces and municipalities except Guangdong Province，that highly-skilled talent cultivation input with the advantage in total scale does not have the same proportional boosting effect on the economic output of regional high-tech industries，that Guangdong Province and Sichuan Province have stronger agglomeration effect on highly-skilled talents，which is worth learning by other provinces and municipalities，however，the input in highly-skilled talent cultivation of Hubei Province and Shaanxi Province does not effectively boost the economic output of high-tech industries in the two provinces，and that it is also worth being focused on how to consolidate the cultivation of highly-skilled talents to work at local provinces and municipalities.