The special system of political centralization of state power and separation d economic power of China has effect on regional cooperation system structure and economic development. According to the characteristics of similar regional endowment conomic development and production skill level, the author uses intermational trade theories and combines the theory with practice to hold that the first step of cooper ation between central and west areas is to provide a unified market system and that the second step is to promote traffic construction in order to provide infrastructure condition for free factors flow of commodity.