In innovative economy, innovative factors and innovative activities are highly agglomerated in space because their flowing is little restricted by resources and environment, and the regional layout of innovative center and the structure of innovative network are highly programmed. Different from the regional integration under the pattern of “core-periphery” formed by industrial agglomeration and diffusion in traditional economy, co-sharing style regional integration is formed because of co-sharing of innovation in innovative economy. As a result, China should actively develop innovative economy, co-construct regional innovative industrial community by all governments, innovative main bodies, production main bodies and so on in the region, optimize innovative ecology by consultative co-governance of each region, by coordinative co-governance of the main body of each industry and by synergic co-governance of government and market, effectively boost the deep integration between innovative chain and industrial chain, sufficiently let innovative diffusion play a promoting role in co-sharing style regional integrated development, and realize high-quality regional integrated development. The Yangtze River delta area should optimize innovative network system, build high-level regional innovative community, promote the deep integration of innovative chain and industrial chain, co-build open industrial community with regional innovation, boost integrated-style institutional innovation, co-manage regional innovative ecology, further realize co-sharing style regional integrated development, and set an example for the integrated development of other regions.