Xiong’an New Area is a model of China’s high-quality development of industry at the new stage of China’s high-quality development. The essence of high-quality development of the industry is to judge the value of industrial development significance and requires for forming new development concept, development objective, development power, evaluation system, supporting environment, operation mechanism and institutional guarantee. Xiong’an New Area wants to take the lead to explore a new path for high quality development of industry, its important and difficult issues lie in narrowing the gap of public service with Beijing, driving traditional industry to transform and upgrade by innovation, cultivating and expanding high-end high-tech industries and playing a model role, and so on, which need to actively explore new development path by “three-new”, “three-high” and “three-combination”. The intrinsic essence of the high-quality development of Xiong’an New Area is to implement new development concept, cultivate new energy and explore new paths, agglomerate high-level innovative factors, develop high-end high-tech industries, build new highland of system and mechanism, combine the undertaking and radiation-driving, combine industrial transformation and industrial upgrading and combine industrial agglomeration and spatial equilibrium. In order to boost the high-quality development of Xiong’an New Area, Hebei should implement new development concept, undertake the non-capital core functions, build economy anti-magnetic center, cultivate and expand high-end high-tech new industry, build industrial innovation ecosystem, give bigger autonomous power to Xiong’an New Area, rationalize the relationship between government and market, construct the system and mechanism conducive to the transformation of scientific research results, build early-warning and prevention mechanism for the risk of high-quality development of industry to provide institutional guarantee for the development.