Moving impoverished population from poverty place to better place is an important measure to solve deep poverty problem in ecological vulnerable area at the stage of hard poverty alleviation and is a complex system project. This paper systematically studies the significance of moving impoverished population from poverty place to better place from the theoretical perspective of interdiction effect, reconstruction effect, growth effect and social unification effect and so on, expounds its restriction conditions from the perspective of integration obstacle, common system dissection effect, living cost constraint, employment difficulty, public service bottle-neck and so on, and takes Guangxi Model as the core to emphatically study its four-dimension core mechanism of “top design-mobilization encouragement-overall coordination-supervision and examination”. The core contents of Guangxi Model contain such nine aspects as infrastructure, employment training, education and medicare, social security, industrial driving, community reconstruction, cultural integration, psychological intervention and ecological recovery so that the systematic institutional framework is built from three-dimension of “economy-society-culture”. These experience and model have certain typicality and are worth summarizing and popularizing.