The prepared orange peel powder, oat flour, skimmed milk powder and xylitol were mixed and formulated. The sensory evaluation of meal fiber replacement powder with orange peel and oat was taken as the index to focus on the effect of the addition of various main raw materials and auxiliary materials on the sensory evaluation data. The optimal formula of the meal fiber replacement powder with orange peel and oat obtained by single factor experiment and orthogonal experiment was o.1g (059%) orange peel powder, 10g (5848%) oat flour, 4g(2339%) skimmed milk powder, and 3g (1754%) xylitol. The meal fiber replacement powder with orange peel and oat flour prepared by this formula has better wetting, sinking and fast dissolving properties and its agglomeration rate is lower. The physical and chemical properties of the product are also better.